- 中文名稱
【SIRT1】重組人SIRT1(193-747 aa)(帶GST標簽)(50個單位)
- 英文名字
- SIRT1 (193-747 aa) (GST-tagged), Human recombinant
- 供應商
- Biovision
- 產品貨號
- 7264-50
- 產品報價
- ¥已停產

- 產品說明書
- 點擊查看
- 購買方式
- 銀行轉賬、電匯、支票、現金,在線支付寶及網銀支付,或直接與我們電話聯系400-6800-868.
- 產品新聞

- 背景資料
- The sirtuins represent a distinct class of trichostatin A-insensitive lysyl-deacetylases (class III HDACs) and have been shown to catalyze a reaction that couples lysine deacetylation to the formation of nicotinamide and O-acetyl-ADP-ribose from NAD+ and the abstracted acetyl group. There are seven human sirtuins, which have been designated SIRT1-7. SIRT1, which is located in the nucleus, is the human sirtuin with the greatest homology to yeast Sir2 (Silent information regulator 2) and has been shown to regulate the activity of the p53 tumor suppressor and inhibit apoptosis. These results have significant implications regarding an important role of SIRT1 in modulating the sensitivity of cells in the p53-dependent apoptotic response and the possible effect in cancer therapy. Since the growth suppressive function of p53 is strongly enhanced by DNA damaging reagents, it is expected that inhibitors of SIRT1 may be effective anti-cancer drugs.
- 序列
- 重組人SIRT1 (193-747 aa) (帶GST標簽)蛋白產品,又稱NAD-dependent Deacetylase 1, SIR2L1, SIR2-like Protein 1, Sirtuin 1, Silent Information Regulator 2.其對應NCBI基因號為23411,對應Accession號為Q96EB6.
- 來源宿主
- 提供的【SIRT1】重組人SIRT1 (193-747 aa) (帶GST標簽)產品的來源為大腸桿菌重組表達.
- 溶解建議
- 重組人SIRT1 (193-747 aa) (帶GST標簽)產品為液體即用型,其溶液組成為:Supplied as a solution in 50 mM sodium phosphate, pH 7.2, containing 100 mM sodium chloride and 20% glycerol
- 保存建議
- 在您收到艾美捷發出的【SIRT1】重組人SIRT1 (193-747 aa) (帶GST標簽)產品后,建議將其置于-80°C保存.
- 其他
- BioVision的公司總部在美麗的舊金山灣地區,它是全球生命科學公司的Leader,BioVision在開發和研究細胞凋亡檢測分析、代謝檢測方面具有卓越的影響力.包括檢測各種檢測分析試劑盒、相關特色抗體、重組蛋白及細胞因子和酶等多種產品,以及其他創新的研究工具.其產品覆蓋細胞凋亡研究、能量代謝、細胞/組織蛋白提取、氧化應激與損傷、代謝與肥胖癥、細胞增殖與毒性、信號轉導、干細胞研究等領域.作為多家知名品牌的中國總代理以及中國區域代理,艾美捷與BioVision一起為研究者們提供優質、新的細胞生物學研究工具而不斷擴大產品及服務質量.

- 注意
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該頁面的中文產品信息的翻譯,僅供參考。準確的產品信息請以廠家的英文說明書為準。下單前,請瀏覽說明書確認。
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