【GFER】人源細胞表達的重組人GFER / HPO / ALR（10微克）-Human CellExp GFER/HPO/ALR, human recombinant代理/參數/廠家-重組蛋白-艾美捷科技有限公司

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背景資料: Growth factor, augmenter of liver regeneration (GFER) is also known as FAD-linked sulfhydryl oxidase ALR, which belongs to the Erv1/ALR family of proteins. This family can be found in higher and lower eukaryotes. There are two isoform of GFER: Isoform 1 and isoform 2. Isoform 2 missing 1 – 80 aa. Isoform 1 is mainly located in mitochondrion intermembrane space, while Isoform 2 is secreted to cytoplasm. Isoform 1 of GFER regenerates the redox-active disulfide bonds in CHCHD4/MIA40, a chaperone essential for disulfide bond formation and protein folding in the mitochondrial intermembrane space. The reduced form of CHCHD4/MIA40 forms a transient intermolecular disulfide bridge with GFER/ERV1, resulting in regeneration of the essential disulfide bonds in CHCHD4/MIA40, while GFER/ERV1 becomes re-oxidized by donating electrons to cytochrome c or molecular oxygen. The isoform 2 of GFER may act as an autocrine hepatotrophic growth factor promoting liver regeneration.

序列: 人源細胞表達的重組人GFER/HPO/ALR蛋白產品，又稱GFER, ALR, ERV1, HERV1, HPO, HPO1, HPO2, HSS, Hepatopoietin.其對應NCBI基因號為2671，對應Accession號為P55789?.

溶解建議: 人源細胞表達的重組人GFER/HPO/ALR產品請按照說明書建議進行溶解操作：Centrifuge the vial prior to opening. Reconstitute in sterile PBS, pH 7.4 to a concentration of 100 ug/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 month. For extended storage, it is recommended to store at -20°C.

其他: BioVision的公司總部在美麗的舊金山灣地區，它是全球生命科學公司的Leader，BioVision在開發和研究細胞凋亡檢測分析、代謝檢測方面具有卓越的影響力.包括檢測各種檢測分析試劑盒、相關特色抗體、重組蛋白及細胞因子和酶等多種產品，以及其他創新的研究工具.其產品覆蓋細胞凋亡研究、能量代謝、細胞/組織蛋白提取、氧化應激與損傷、代謝與肥胖癥、細胞增殖與毒性、信號轉導、干細胞研究等領域.作為多家知名品牌的中國總代理以及中國區域代理，艾美捷與BioVision一起為研究者們提供優質、新的細胞生物學研究工具而不斷擴大產品及服務質量.