The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth. Many BMPs are part of the transforming growth factor-beta (TGFB) superfamily. BMPs were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extra skeletal site. Based on its expression early in embryogenesis, the BMP encoded by this gene has a proposed role in early development. In addition, the fact that this BMP is closely related to BMP5 and BMP7 has led to speculation of possible bone inductive activity. Recombinant human BMP8B protein, fused to His-tag at N-terminus, was expressed in E.coli.
序列
重組人骨形態發生蛋白8B蛋白產品，又稱BMP8, OP2, Bone morphogenetic protein 8B.其對應NCBI基因號為656，對應Accession號為P34820.
來源宿主
提供的【BMP8B】重組人骨形態發生蛋白8B產品的來源為大腸桿菌重組表達.
溶解建議
重組人骨形態發生蛋白8B產品為液體即用型，其溶液組成為：1 mg/ml in 20 mM Tris-HCl buffer (pH 8.0) containing 0.4 M Urea and 10% glycerol
