IGFBP6 contains 1 IGFBP N-terminal domain and 1 thyroglobulin type-1 domain. IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Recombinant human IGFPB6 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
序列
重組人胰島素樣生長因子-BP6蛋白產品,又稱Insulin-like growth factor-binding protein 6, IBP6.其對應NCBI基因號為3489,對應Accession號為P24592.
來源宿主
提供的【IGFBP6】重組人胰島素樣生長因子-BP6產品的來源為大腸桿菌重組表達.
溶解建議
重組人胰島素樣生長因子-BP6產品為液體即用型,其溶液組成為:0.5 mg/ml in 20 mM Tris-HCl buffer (pH 8.0) containing 0.15 M NaCl, 1 mM DTT and 20% glycerol.