【TNFRSF10B】人源細胞表達的重組人瘤壞死因子受體超家族成員10B / TRAILR2（50 ug）-Human CellExp TNFRSF10B /TRAILR2, human recombinant代理/參數/廠家-重組蛋白-艾美捷科技有限公司

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背景資料: Tumor necrosis factor receptor superfamily member 10B (TNFRSF10B) also known as TNF-related apoptosis-inducing ligand receptor 2 (TRAILR2), Death receptor 5 (DR5), CD262, KILLER, is a member of the TNF-receptor superfamily, and contains an intracellular death domain. TNFRSF10B / DR-5 is widely expressed in adult and fetal tissues; very highly expressed in tumor cell lines. TRAILR2 / CD262 / DR5 is the receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter molecule FADD (a death domain containing adaptor protein) of TRAIL-R2 / TNFRSF10B recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. CD262 / DR5 Promotes the activation of NF-kappa-B. DR5 is essential for ER stress-induced apoptosis and is regulated by p53/TP53.

序列: 人源細胞表達的重組人瘤壞死因子受體超家族成員10B/TRAILR2蛋白產品，又稱TNFRSF10B, TRAILR2, TRAIL-R2, CD262, DR5, KILLER, TRICK2, ZTNFR9, TRICKB.其對應NCBI基因號為8795，對應Accession號為O14763.

來源宿主: 提供的【TNFRSF10B】人源細胞表達的重組人瘤壞死因子受體超家族成員10B/TRAILR2產品的來源為人胚腎HEK293細胞重組表達重組表達.

溶解建議: 人源細胞表達的重組人瘤壞死因子受體超家族成員10B/TRAILR2產品請按照說明書建議進行溶解操作：Centrifuge the vial prior to opening. Reconstitute in sterile PBS, pH 7.4 to a concentration of 50 ug/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 month. For extended storage, it is recommended to store at -20°C.

保存建議: 在您收到艾美捷發出的【TNFRSF10B】人源細胞表達的重組人瘤壞死因子受體超家族成員10B/TRAILR2產品后，建議將其置于-20°C保存.

其他: BioVision的公司總部在美麗的舊金山灣地區，它是全球生命科學公司的Leader，BioVision在開發和研究細胞凋亡檢測分析、代謝檢測方面具有卓越的影響力.包括檢測各種檢測分析試劑盒、相關特色抗體、重組蛋白及細胞因子和酶等多種產品，以及其他創新的研究工具.其產品覆蓋細胞凋亡研究、能量代謝、細胞/組織蛋白提取、氧化應激與損傷、代謝與肥胖癥、細胞增殖與毒性、信號轉導、干細胞研究等領域.作為多家知名品牌的中國總代理以及中國區域代理，艾美捷與BioVision一起為研究者們提供優質、新的細胞生物學研究工具而不斷擴大產品及服務質量.