Calreticulin is involved in regulation of intracellular Ca2+ homoeostasis and ER Ca2+ capacity. It constitutes together with calnexin and ERp57 the ‘calreticulin/calnexin cycle’ that is responsible for folding and quality control of newly synthesized glycoproteins. Calreticulin has been implicated to play a role in many biological systems, including functions inside and outside the ER, indicating that the protein is a multi-process molecule. Recently, Calreticulin was shown to enhance the merger of macrophages and tumor cells, increasing phagocytosis.
序列
重組人鈣網蛋白蛋白產品，又稱CRP55; Calregulin; Endoplasmic Reticulum Resident Protein 60; ERp60; grp60.其對應NCBI基因號為811，對應Accession號為P27797.
來源宿主
提供的【Calreticulin】重組人鈣網蛋白產品的來源為大腸桿菌重組表達.
溶解建議
重組人鈣網蛋白產品為液體即用型，其溶液組成為：0.2 um-filtered solution in 55 mM Tris-Cl, pH 8.2, containing 150 mM NaCl.
