Irisin is a recently described exercise-induced hormone secreted by skeletal muscle in mice and humans. Irisin activates beige fat cells (beige cells have a gene expression pattern distinct from either white or brown fat and are preferentially sensitive to the polypeptide hormone Irisin). Irisin is cleaved from the type I membrane protein FNDC5 and improves systemic metabolism by increasing energy expenditure. FNDC4 is an ortholog of FNDC5 with 50% identity and 86% similarity compared to Irisin. FNDC4 as well as FNDC5 are extremely well conserved between species. The function of FNDC4 is unknown. The human FNDC4 gene is highly enriched in liver, brain tissue and adipocytes.
序列
重組人/小鼠FNDC4蛋白產品，又稱Fibronectin Type III Domain-containing Protein 4; Fibronectin Type III Repeat-containing Protein 1.其對應NCBI基因號為64838，對應Accession號為Q9H6D8.
來源宿主
提供的【FNDC4】重組人/小鼠FNDC4產品的來源為大腸桿菌重組表達.
溶解建議
重組人/小鼠FNDC4產品請按照說明書建議進行溶解操作：Reconstitute with 100 ul sterile distilled water.
