UNC5B is a receptor for the netrin family of guidance molecules. It was identified as a mediator of the repulsive response in neurons and it is the only known netrin receptor with prominent endothelial expression. It has an important role in angiogenesis signaling.
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人源細胞表達的重組人UNC5B蛋白產品,又稱Netrin Receptor UNC5B; UNC5H2; Protein Unc-5 Homolog 2; Protein Unc-5 Homolog B; p53-regulated Receptor for Death and Life Protein 1.其對應NCBI基因號為219699,對應Accession號為Q8IZJ1.