TACE (TNF-alpha converting enzyme, ADAM17) is a membrane-bound Metalloprotease from the ADAM (a disintegrin and Metalloprotease) family of proteins. It cleaves 26kDa type II membrane-bound precursor of TNF-a into 17 kDa mature form which is secreted. TACE is also known to process other membrane proteins including TNF receptor, TGF-alpha and amyloid protein precursor. Recombinant active untagged TACE amino acid sequence is from Arg215 to Asn651. The apparent molecular weight is bigger than the calculated MW due to the protein posttranslational modification in eukaryotic system.
序列
重組人TACE (TNF-α轉化酶)蛋白產品，又稱Disintegrin and metalloproteinase domain-containing protein 17, ADAM 17, Snake venom-like protease, TNF-alpha convertase, TNF-alpha-converting enzyme.其對應NCBI基因號為6868，對應Accession號為P78536.
來源宿主
提供的【TACE】重組人TACE (TNF-α轉化酶)產品的來源為昆蟲細胞重組表達.
溶解建議
重組人TACE (TNF-α轉化酶)產品請按照說明書建議進行溶解操作：With sterile deionized water at 0.1ug protein/ul.
