The acetylation of histone lysine residues plays a crucial role in the epigenetic regulation of gene transcription. A bromodomain is a protein domain that recognizes acetylated lysine residues such as those on the N-terminal tails of histones. This recognition is often a prerequisite for protein-histone association and chromatin remodeling. These domains function in the linking of protein complexes to acetylated nucleosomes, thereby controlling chromatin structure and gene expression. Thus, bromodomains serve as “readers” of histone acetylation marks regulating the transcription of target promoters. WDR9 possesses two bromodomain motifs and eight WD repeats. WDR9 is also known to interact with BRG1 (SMARCA4). This product contains the bromodomain 2 region of WDR9.
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重組人WRD9 bromodomain結構域2 (1310-1426 aa) (帶GST標簽)蛋白產品，又稱BRD and WD repeat-containing protein 1; WD repeat-containing protein 9.其對應NCBI基因號為54014，對應Accession號為Q9NSI6.
重組人WRD9 bromodomain結構域2 (1310-1426 aa) (帶GST標簽)產品為液體即用型，其溶液組成為：50 mM Tris, pH 7.5, containing 500 mM sodium chloride, 5% glycerol, and 5 mM β-mercaptoethanol.
