【纖維蛋白原】天然人血漿纖維蛋白原（Pg，Fn和vWF耗盡）（250 mg）-Fibrinogen (Pg, Fn & vWF depleted), Human Plasma代理/參數/廠家-重組蛋白-艾美捷科技有限公司

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背景資料: Fibrinogen is an acute phase protein that is part of the coagulation cascade of proteins. The end result of the cascade is the production of thrombin that converts fibrinogen to fibrin. Thrombin rapidly proteolysis fibrinogen, releasing fibrinopeptide A. The loss of this small peptide is not sufficient to make the resulting fibrin molecule insoluble, but it tends to form complexes with adjacent fibrin and fibrinogen molecules. Thrombin then cleaves a second peptide, fibrinopeptide B, from fibrin and the fibrin monomers formed then polymerize spontaneously to form an insoluble gel. The polymerized fibrin is held together by noncovalent and electrostatic forces and stabilized by the transamidating enzyme, factor XIIIa that is produced by the action of thrombin on factor XIII. The insoluble fibrin aggregates (clots) and aggregated platelets then block the damaged blood vessel and prevent further bleeding. The amount of fibrinogen in the plasma can serve as a nonspecific indicator of whether or not an inflammatory process is present in the body. Fibrinogen from any mammalian source will be cleaved by thrombin from any mammalian source.

序列: 天然人血漿 Fibrinogen (Pg, Fn & vWF depleted)蛋白產品，又稱Factor 1.其對應NCBI基因號為2243，對應Accession號為P02671.

溶解建議: 天然人血漿 Fibrinogen (Pg, Fn & vWF depleted)產品為液體即用型，其溶液組成為：In 20 mM Sodium Citrate-HCl pH 7.4.

保存建議: 在您收到艾美捷發出的【Fibrinogen 】天然人血漿 Fibrinogen (Pg, Fn & vWF depleted)產品后，建議將其置于-80°C保存.

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