- 中文名稱
【Pim 1】Pim 1蛋白,有活性的(5 ug)
- 英文名字
- Pim 1, Active
- 供應商
- Biovision
- 產品貨號
- 7742-5
- 產品報價
- ¥已停產

- 產品說明書
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- 購買方式
- 銀行轉賬、電匯、支票、現金,在線支付寶及網銀支付,或直接與我們電話聯系400-6800-868.
- 產品新聞

- 背景資料
- The proto-oncogene Pim1 belongs to a family of serine/threonine protein kinases that are highly conserved through evolution in multicellular organisms. Originally identified from Moloney murine leukemia virus induced T-cell lymphomas in mice, Pim1 is involved in the control of cytokine-mediated cell proliferation, differentiation and survival of lymphoid and myeloid cells as well as others. Expression of Pim1 can be stimulated by a variety of growth factors and is regulated at four different levels: transcriptional, post-transcriptional, translational and post-translational. Accumulating data support that the expression of Pim1 is mediated through activation of the JAK/STAT pathway. Some of the substrates of Pim1 include p21 Cip1, nuclear mitotic appartus protein, PTP-U2S and Socs-1. Recently, Pim1 has been shown to enhance the activities of p100, c-Myb and Cdc 25a and in part this might explain reported effects of Pim1 on mitogenesis. Pim1 interacts with c-Myb via the DNA binding domain and regulates its transcriptional activity.
- 序列
- Pim 1蛋白,有活性的蛋白產品,又稱Pim, Serine/threonine-protein kinase Pim-1.其對應NCBI基因號為5595,NCBI基因別稱為ERK1源,對應Accession號為P27361.該蛋白產品又稱pim1, pim-1, Active Pim 1, Pim 1, Pim, human Pim, active kinase, active kinases, recombinant Pim 1, recombinant Pim, kinase activity assay, protein kinase等.
- 來源宿主
- 提供的【Pim 1】Pim 1蛋白,有活性的產品的來源為Sf9昆蟲細胞-桿狀病毒中重組表達.
- 溶解建議
- 提供的Pim 1蛋白,有活性的 產品為液態形式溶解于儲存液(50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 0.25 mM DTT, 0.1 mM EGTA, 0.1 mM EDTA, 0.1 mM PMSF, 25% 甘油)中.
- 保存建議
- 在您收到艾美捷發出的【Pim 1】Pim 1蛋白,有活性的產品后,建議將其置于-80°C保存.
- 其他
- BioVision的公司總部在美麗的舊金山灣地區,它是全球生命科學公司的Leader,BioVision在開發和研究細胞凋亡檢測分析、代謝檢測方面具有卓越的影響力.包括檢測各種檢測分析試劑盒、相關特色抗體、重組蛋白及細胞因子和酶等多種產品,以及其他創新的研究工具.其產品覆蓋細胞凋亡研究、能量代謝、細胞/組織蛋白提取、氧化應激與損傷、代謝與肥胖癥、細胞增殖與毒性、信號轉導、干細胞研究等領域.作為多家知名品牌的中國總代理以及中國區域代理,艾美捷與BioVision一起為研究者們提供優質、新的細胞生物學研究工具而不斷擴大產品及服務質量.

- 注意
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該頁面的中文產品信息的翻譯,僅供參考。準確的產品信息請以廠家的英文說明書為準。下單前,請瀏覽說明書確認。
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