Glycoprotein that belongs to a family which takes part in the activation and regulation of the MMP-activity. Forms a non-covalent stoichiometric complex with latent and active MMP's. Inhibits the activities of MMP-1, MMP-2, MMP-12 and transin.
序列
天然人成纖維細胞基質金屬蛋白酶抑制物-2蛋白產品,又稱Metalloproteinase inhibitor 2 (CSC-21K) (Tissue inhibitor of metalloproteinases 2) (TIMP-2).其對應NCBI基因號為7077,對應Accession號為P16035.
來源宿主
提供的【TIMP2】天然人成纖維細胞基質金屬蛋白酶抑制物-2產品的來源為人成纖維細胞中分離.
溶解建議
天然人成纖維細胞基質金屬蛋白酶抑制物-2產品為液體即用型,其溶液組成為:In 50 mM Tris-HCl, pH 7; 200 mM NaCl; 5 mM CaCl?; 1 uM ZnCl?; 0.05% Brij 35; 0,05% NaN?