DuSP21 (Dual specificity protein phosphatase 21) belongs to the protein-tyrosine phosphatase family. Dual specificity protein phosphatases (DuSPs) inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. This enzyme can dephosphorylate single and diphosphorylated synthetic MAPK peptides, with preference for the phosphotyrosine and diphosphorylated forms over phosphothreonine. It is exclusively expressed in testis where is preferentially dephosphorylates phosphotyrosine residues in MAPK peptides. Recombinant human DuSP21 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
序列
重組人DUSP21蛋白產品，又稱Dual specificity protein phosphatase 21.其對應NCBI基因號為63904，對應Accession號為Q9H596.
來源宿主
提供的【DUSP21】重組人DUSP21產品的來源為大腸桿菌重組表達.
溶解建議
重組人DUSP21產品為液體即用型，其溶液組成為：0.25 mg/ml solution in 20 mM Tris-HCl buffer (pH 8.0) containing 20% glycerol, 200 mM NaCl and 2 mM DTT
