HAGH is a member of the glyoxalase family and a thiolesterase which hydrolyses S-lactoyl-glutathione to reduced glutathione and D-lactate. This protein is a detoxifying enzyme of glycolysis byproduct methylglyoxal and a target of p63 and p73 and serves as a pro-survival factor of the p53 family. It exists only as a monomer and binds two zinc ions per subunit. Recombinant human HAGH protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.
序列
重組人HAGH蛋白產品，又稱Hydroxyacylglutathione hydrolase, GLO, GLX2, Glyoxalase II, HAGH1.其對應NCBI基因號為3029，對應Accession號為Q16775.
來源宿主
提供的【HAGH】重組人HAGH產品的來源為大腸桿菌重組表達.
溶解建議
重組人HAGH產品為液體即用型，其溶液組成為：0.5 mg/ml solution in 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol
