- 中文名稱
【CYP2C19】(生物活性)人源細胞色素P450 2C19
- 英文名字
- EZCyp? Active Human Cytochrome P450 2C19
- 供應商
- Biovision
- 產品貨號
- 7874-50
- 產品報價
- ¥已停產

- 產品說明書
- 點擊查看
- 購買方式
- 銀行轉賬、電匯、支票、現金,在線支付寶及網銀支付,或直接與我們電話聯系400-6800-868.
- 產品新聞

- 背景資料
- Cytochrome P450 2C19 (CYP2C19, EC 1.14.14.1) is a member of the cytochrome P450 monooxidase (CYP) family of microsomal xenobiotic metabolism enzymes. CYPs are membrane-bound hemeproteins responsible for Phase I biotransformation reactions, in which lipophilic drugs and other xenobiotic compounds are converted to more hydrophilic products to facilitate excretion from the body. CYP2C19 is primarily expressed in liver and intestinal tissue and catalyzes oxidation of neutral or weakly basic lipophilic molecules with 2-3 hydrogen bond donor/acceptor sites. Isoforms of the CYP2C subfamily are responsible for metabolism of nearly 20% of all small molecule drugs commonly used by humans. Polymorphisms in the human CYP2C19 gene have been implicated in clinical drug/drug interactions involving widely-prescribed drugs, including proton pump inhibitors, antiplatelet agents and anticonvulsants. BioVision’s EZCypTM 2C19 is a permeabilized and stabilized dried yeast powder preparation containing recombinant human CYP2C19 and recombinant human P450 NADPH oxidoreductase co expressed in the same preparation.
- 序列
- (生物活性)人源細胞色素P450 2C19又稱Cytochrome P450 2C, Cytochrome P450 2C19, Cyt2C19, CYPIIC, CYPIIC19, Cyp2c, Microsomal cytochrome P450 2C19, active CYP2C19, human cyp2c19, human CYP2C19, CPCJ, recombinant CYP2C, P450C2C, CYPIIC17, CYPIIC19, P450IIC19.其對應NCBI基因號為1557,對應Accession號為P33261.
- 來源宿主
- 提供的【CYP2C19】(生物活性)人源細胞色素P450 2C19蛋白產品來源為畢赤酵母中重組表達.
- 溶解建議
- 提供的(生物活性)人源細胞色素P450 2C19產品為固體凍干粉形式.溶解于50 mM磷酸鉀緩沖液中, pH 7.7
- 保存建議
- 艾美捷推薦冰袋運輸【CYP2C19】(生物活性)人源細胞色素P450 2C19產品.我們建議您收到該產品后將其置于-20°C保存.產品有效期為收到產品后12個月.
- 其他
- BioVision的公司總部在美麗的舊金山灣地區,它是全球生命科學公司的Leader,BioVision在開發和研究細胞凋亡檢測分析、代謝檢測方面具有卓越的影響力.包括檢測各種檢測分析試劑盒、相關特色抗體、重組蛋白及細胞因子和酶等多種產品,以及其他創新的研究工具.其產品覆蓋細胞凋亡研究、能量代謝、細胞/組織蛋白提取、氧化應激與損傷、代謝與肥胖癥、細胞增殖與毒性、信號轉導、干細胞研究等領域.作為多家知名品牌的中國總代理以及中國區域代理,艾美捷與BioVision一起為研究者們提供優質、新的細胞生物學研究工具而不斷擴大產品及服務質量.

- 注意
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