Recombinant Mouse Sonic Hedgehog is a member of a small group of secreted proteins that are essential for development in both vertebrates and invertebrates. Three mammalian hedgehog genes (sonic, desert, Indian) share about 60% homology. The Mouse Sonic Hedgehog is 99% homologous to the human gene. Cysteine at position 25 has been substituted with Ile. Mouse SHH is a non-glycosylated polypeptide consisting of 176 amino acids with a molecular weight of 19,800 Da.
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重組小鼠音猬因子又稱SHH; HHG1; HLP3; HPE3; SMMCI, Sonic hedgehog.其對應NCBI基因號為20423,對應Accession號為Q8C765.