The MKI67 gene encodes a nuclear protein termed Ki-67 that is associated with and may be necessary for cellular proliferation. Alternatively spliced transcript variants have been described. A related pseudogene exists on chromosome X. Two isoforms have been reported, with isoform 1 transcribed as the longer transcript. Ki-67 is a nuclear protein predominantly localized in the G1 phase in the perinucleolar region. In later phases it is also detected throughout the nuclear interior, being predominantly localized in the nuclear matrix. In mitosis, it is present on all chromosomes.
應用類型
ELISA,Immunohistochemistry,Western Blot,
免疫原
This monoclonal antibody was produced by repeated immunizations with a synthetic peptide corresponding to the carboxy terminus of human Ki-67 protein. The hybridoma was produced by fusing New Zealand White rabbit splenocytes and myeloma cells using conventional technology.
來源宿主
Rabbit
反應性
H. sapiens (Human); Rattus (Rat)
保存建議
Store at 2-8°C. Do not freeze. The user must validate any other storage conditions. When properly stored, the reagent is stable to the date indicated on the label. Do not use the reagent beyond the expiration date.
