CSTB, also known as Cystatin B is an anti-protease implicated in myoclonus epilepsy, a degenerative disease of the central nervous system. The cystatin superfamily encompasses proteins that contain multiple cystatin like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. This protein is able to form a dimer stabilized by noncovalent forces and is thought to play a role in protecting against the proteases leaking from lysosomes. In cells, CSTB is located in the lysosomes and the cytoplasm, but also in the nucleus.
序列
提供的CSTB,人類重組CSTB, human recombinant是Biovision品牌中國區域總代理艾美捷科技產品,具體的蛋白序列可查看提供的英文版本產品說明書。
來源宿主
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溶解建議
In 20 mM Tris-HCl buffer (pH8.0) containing 50mM NaCl.