NKH477(5毫克)產品是NKH477 is a water-soluble analog of the adenylyl cyclase activator Forskolin (Cat. No. 1531). Like forskolin, NKH477 activates adenylyl cyclases without altering the activity of phosphodiesterases or sodium/potassium ATPases.?It stimulates cardiac (type V) adenylyl cyclase more potently than other isoforms. NKH477 relaxes guinea pig tracheal smooth muscle precontracted with histamine with an EC50?value of 32.6 nM.