GW-7647(25毫克)產品是GW-7647 is a potent, selective agonist of human and murine PPARα.?It activates human PPARα, PPARγ, and PPARδ with EC???values of 0.006, 1.1 and 6.2 uM, respectively, in a GAL4-PPAR binding assay. Similar EC???values of 0.001, 1.3, and 2.9 were observed with the murine receptors.?Modulates oleate metabolism and mitochondrial enzyme gene expression in mature myotubules?in vitro. Has lipid-lowering effects following oral administrationin vivo. Reduces NO production in macrophages; exhibits anti-inflammatory properties.