P505-15(5毫克)產品是P505-15 is a potent, cell-permeable, highly selective, small molecule SYK inhibitor (IC?? = 1 nM) with anti-SYK activity that is at least 80-fold greater than its affinity for other kinases. ?P505-15 blocks B cell receptor-mediated cell signaling and activation in whole blood (IC??s = 0.27 and 0.28 uM, respectively), as well as Fc? receptor 1-mediated basophil degranulation (IC???= 0.15 uM).