PS-1145產品是PS-1145 is a potent and selective IκB kinase (IKK) inhibitor (IC?? = 100 nM). Has no effect on PKA, PKC and CKII activity.?PS-1145 efficiently inhibits both basal and induced NF-κB activity in PC cells. Enhances TNF-α-induced apoptosis in a multiple myeloma cell line.