- 中文名稱
GEMIN7抗體- N端 (AI16069)
- 英文名字
- GEMIN7 Antibody - N-terminal region (AI16069)
- 供應商
- Abgent
- 產品貨號
- A-AI16069
- 產品報價
- ￥3750/50 ug
- 產品說明書
- 點擊查看
- 購買方式
- 產品新聞
- 背景資料
- The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. In the cytosol, the Sm proteins SNRPD1, SNRPD2, SNRPE, SNRPF and SNRPG are trapped in an inactive 6S pICln-Sm complex by the chaperone CLNS1A that controls the assembly of the core snRNP. Dissociation by the SMN complex of CLNS1A from the trapped Sm proteins and their transfer to an SMN-Sm complex triggers the assembly of core snRNPs and their transport to the nucleus.
- 應用類型
- WB
- 免疫原
- Q9H840
- 來源宿主
- 反應性
- 保存建議
- 其他
- ABGENT
- 注意
-
該頁面的中文產品信息的翻譯，僅供參考。準確的產品信息請以廠家的英文說明書為準。下單前，請瀏覽說明書確認。
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