This gene encodes a member of the tumor protein D52
(TPD52) family. The encoded protein contains a coiled-coil domain
and may form homo- or hetero-dimer with TPD52 family members. The
protein is reported to be involved in cell proliferation and
calcium signaling. It also interacts with the mitogen-activated
protein kinase kinase kinase 5 (MAP3K5/ASK1) and positively
regulates MAP3K5-induced apoptosis. Multiple alternatively spliced
transcript variants have been observed, but the full-length nature
of some variants has not yet been determined.
