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中文名稱

KDELR1抗體(C端)

英文名字
KDELR1 Antibody (C-term)
供應商
Abgent
產品貨號
A-AP19130b
產品報價
¥2310/400 ul
產品說明書
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背景資料
Retention of resident soluble proteins in the lumen of the
endoplasmic reticulum (ER) is achieved in both yeast and animal
cells by their continual retrieval from the cis-Golgi, or a
pre-Golgi compartment. Sorting of these proteins is dependent on a
C-terminal tetrapeptide signal, usually lys-asp-glu-leu (KDEL) in
animal cells, and his-asp-glu-leu (HDEL) in S. cerevisiae. This
process is mediated by a receptor that recognizes, and binds the
tetrapeptide-containing protein, and returns it to the ER. In
yeast, the sorting receptor encoded by a single gene, ERD2, which
is a seven-transmembrane protein. Unlike yeast, several human
homologs of the ERD2 gene, constituting the KDEL receptor gene
family, have been described. The protein encoded by this gene was
the first member of the family to be identified, and it encodes a
protein structurally and functionally similar to the yeast ERD2
gene product.
應用類型
WB
免疫原
P24390
來源宿主
反應性
保存建議
其他
ABGENT
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