乙?；嚢彼?單克隆抗體-Acetyl Lysine Monoclonal Antibody代理/參數/廠家-一抗-艾美捷科技有限公司

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背景資料: amino-terminal domains of the four core histones (H2A, H2B, H3, and H4) contain lysines that are acetylated by histone acetyltransferases (HATs) and deacetylated by histone deacetylases (HDACs) . Signaling resulting in acetylation/deacetylation of histones, transcription factors, and other proteins affects a diverse array of cellular processes including chromatin structure and gene activity, cell growth, differentiation, and apoptosis . Recent proteomic surveys suggest that acetylation of lysine residues may be a widespread and important form of posttranslational protein modification that affects thousands of proteins involved in control of cell cycle and metabolism, longevity, actin polymerization, and nuclear transport . The regulation of protein acetylation status is impaired in cancer and polyglutamine diseases , and HDACs have become promising targets for anti-cancer drugs currently in development .
蛋白別名為：Lysine;

應用類型: WB，IHC-p
補充：最優的抗體稀釋比例需要基于客戶實驗進行優化.建議的起始稀釋比例如下: WB: 1:1000-2000, IHC-p: 1:200-500.

保存建議: 廠家推薦藍冰運輸.在發貨后能在-20℃保存1年.為最大限度的避免損失，請在打開管蓋之前融化抗體并離心.我們建議使用前分裝以避免反復凍融.
本產品為液體形式,溶解于PBS緩沖液（pH 7.4）中, 含有0.02%NaN3的防腐劑和50%甘油.

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