The protein encoded by ITGA7 belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. They mediate a wide spectrum of cell-cell and cell-matrix interactions, and thus play a role in cell migration, morphologic development, differentiation, and metastasis.Integrin subunit alpha 7 functions as a receptor for the basement membrane protein laminin-1. It is mainly expressed in skeletal and cardiac muscles and may be involved in differentiation and migration processes during myogenesis. Defects in ITGA7 are associated with congenital myopathy. Alternatively spliced transcript variants encoding different isoforms have been noted for ITGA7.蛋白別名為：ITGA7; Integrin alpha-7;基因ID為：3679；蛋白質ID:Q13683
應用類型
WB，ELISA補充：最優的抗體稀釋比例需要基于客戶實驗進行優化.建議的起始稀釋比例如下: WB: 1:500-1:2000, ELISA: 1:40000. Not yet tested in other applications.
免疫原
合成多肽：the C-terminal region of human Integrin α7 LC. at AA rangle: 910-990
