Janus kinase 2 is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways. It has been found to be constituitively associated with the prolactin receptor and is required for responses to gamma interferon. Mice that do not express an active protein for JAK2 exhibit embryonic lethality associated with the absence of definitive erythropoiesis.蛋白別名為:JAK2; Tyrosine-protein kinase JAK2; Janus kinase 2; JAK-2;基因ID為:3717;蛋白質ID:O60674
應用類型
WB,IHC-p,ELISA補充:最優的抗體稀釋比例需要基于客戶實驗進行優化.建議的起始稀釋比例如下: IHC-p: 1:100-1:300, ELISA: 1:20000. Not yet tested in other applications.
免疫原
合成多肽:human JAK2 around the phosphorylation site of Y1007.