EPOR encodes the erythropoietin receptor（erythropoietin receptor） which is a member of the cytokine receptor family. Upon erythropoietin binding, this receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis. Dysregulation of EPOR may affect the growth of certain tumors. Alternate splicing results in multiple transcript variants.蛋白別名為：EPOR; Erythropoietin receptor; EPO-R;基因ID為：2057；蛋白質ID:P19235
應用類型
WB，ELISA補充：最優的抗體稀釋比例需要基于客戶實驗進行優化.建議的起始稀釋比例如下: WB: 1:500-1:2000, ELISA: 1:20000. Not yet tested in other applications.
免疫原
合成多肽：human EpoR around the phosphorylation site of Y426.
