AASS encodes a bifunctional enzyme (aminoadipate-semialdehyde synthase)that catalyzes the first two steps in the mammalian lysine degradation pathway. The N-terminal and the C-terminal portions of this enzyme contain lysine-ketoglutarate reductase and saccharopine dehydrogenase activity, respectively, resulting in the conversion of lysine to alpha-aminoadipic semialdehyde. Mutations in AASS are associated with familial hyperlysinemia. 蛋白別名為:AASS; Alpha-aminoadipic semialdehyde synthase; mitochondrial; LKR/SDH;基因ID為:10157;蛋白質ID:Q9UDR5
應用類型
WB,ELISA補充:最優的抗體稀釋比例需要基于客戶實驗進行優化.建議的起始稀釋比例如下: WB: 1:500-1:2000, ELISA: 1:10000. Not yet tested in other applications.
免疫原
合成多肽:the Internal region of human AASS. at AA rangle: 220-300