The membrane-associated protein encoded by ABCA6 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White). This encoded protein(ATP binding cassette subfamily A member 6) is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. ABCA6 is clustered among 4 other ABC1 family members on 17q24 and may play a role in macrophage lipid homeostasis.蛋白別名為:ABCA6; ATP-binding cassette sub-family A member 6;基因ID為:23460;蛋白質ID:Q8N139
應用類型
WB,ELISA補充:最優的抗體稀釋比例需要基于客戶實驗進行優化.建議的起始稀釋比例如下: WB: 1:500-1:2000, ELISA: 1:40000. Not yet tested in other applications.
免疫原
合成多肽:the C-terminal region of human ABCA6. at AA rangle: 1180-1260