ABCC12 is a member of the superfamily of ATP-binding cassette (ABC) transporters and the encoded protein(ATP binding cassette subfamily C member 12) contains two ATP-binding domains and 12 transmembrane regions. ABC proteins transport various molecules across extra- and intracellular membranes.ABC genes are divided into seven distinct subfamilies: ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White. ABCC12 is a member of the MRP subfamily which is involved in multi-drug resistance. ABCC12 and another subfamily member are arranged head-to-tail on chromosome 16q12.1. Increased expression of ABCC12 is associated with breast cancer. 蛋白別名為:ABCC12; MRP9; Multidrug resistance-associated protein 9; ATP-binding cassette sub-family C member 12;基因ID為:94160;蛋白質ID:Q96J65
應用類型
WB,ELISA補充:最優的抗體稀釋比例需要基于客戶實驗進行優化.建議的起始稀釋比例如下: WB: 1:500-1:2000, ELISA: 1:20000. Not yet tested in other applications.
免疫原
合成多肽:the Internal region of human ABCC12. at AA rangle: 730-810