ACAT1 encodes a mitochondrially localized enzyme(acetyl-CoA acetyltransferase 1) that catalyzes the reversible formation of acetoacetyl-CoA from two molecules of acetyl-CoA. Defects in ACAT1 are associated with 3-ketothiolase deficiency, an inborn error of isoleucine catabolism characterized by urinary excretion of 2-methyl-3-hydroxybutyric acid, 2-methylacetoacetic acid, tiglylglycine, and butanone.蛋白別名為:ACAT1; ACAT; MAT; Acetyl-CoA acetyltransferase; mitochondrial; Acetoacetyl-CoA thiolase; T2;基因ID為:38;蛋白質ID:P24752
應用類型
WB,IHC-p,ELISA補充:最優的抗體稀釋比例需要基于客戶實驗進行優化.建議的起始稀釋比例如下: WB: 1:500-1:2000, IHC-p: 1:100-1:300, ELISA: 1:40000. Not yet tested in other applications.
免疫原
合成多肽:the Internal region of human ACAT-1. at AA rangle: 190-270