BLK encodes a nonreceptor tyrosine-kinase of the src family of proto-oncogenes that are typically involved in cell proliferation and differentiation. The protein(BLK proto-oncogene, Src family tyrosine kinase) has a role in B-cell receptor signaling and B-cell development. The protein also stimulates insulin synthesis and secretion in response to glucose and enhances the expression of several pancreatic beta-cell transcription factors.蛋白別名為:BLK; Tyrosine-protein kinase Blk; B lymphocyte kinase; p55-Blk;基因ID為:640;蛋白質ID:P51451
應用類型
WB,IHC-p,ELISA補充:最優的抗體稀釋比例需要基于客戶實驗進行優化.建議的起始稀釋比例如下: IHC-p: 1:100-1:300, ELISA: 1:40000. Not yet tested in other applications.
免疫原
合成多肽:human Blk around the non-phosphorylation site of Y501.