BCLAF1encodes a transcriptional repressor that interacts with several members of the BCL2 family of proteins. Overexpression of this protein(BCL2 associated transcription factor 1)induces apoptosis, which can be suppressed by co-expression of BCL2 proteins. The protein localizes to dot-like structures throughout the nucleus, and redistributes to a zone near the nuclear envelope in cells undergoing apoptosis. Multiple transcript variants encoding different isoforms have been found for BCLAF1.蛋白別名為:BCLAF1; BTF; KIAA0164; Bcl-2-associated transcription factor 1; Btf;基因ID為:9774;蛋白質ID:Q9NYF8
應用類型
WB,ELISA補充:最優的抗體稀釋比例需要基于客戶實驗進行優化.建議的起始稀釋比例如下: WB: 1:500-1:2000, ELISA: 1:10000. Not yet tested in other applications.
免疫原
合成多肽:the Internal region of human BTF. at AA rangle: 250-330