Cerebellin 2 多克隆抗體-Cerebellin 2 Polyclonal Antibody代理/參數/廠家-一抗-艾美捷科技有限公司

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背景資料: Cerebellin (CER), which was originally isolated from rat cerebellum, is a hexadecapeptide derived from a larger precursor Cerebellin 1, also designated precerebellin 1 or Cbln1. Four propeptides, Cerebellin 1, Cerebellin 2 (Cbln2), Cerebellin 3 (Cbln3), and Cerebellin 4 (Cbln4), comprise the precerebellin subfamily within the C1q protein family. Cerebellin family members act as transneuronal regulators of synapse development and synaptic plasticity in various brain regions. CER and it metabolite des-Ser1-cerebellin are also expressed in several extra-cerebellar tissues, including adrenal gland. Cerebellin 1, 2 and 3 assemble into homomeric and heteromeric complexes, thereby influencing each other's degradation and secretion. Cerebellin 3 is not able to form homomeric complexes, and can only be secreted upon forming a heteromeric complex with Cerebellin 1. Decreased concentrations of CER has been found in the brain of patients with olivopontocerebellar atrophy (OPCA) and Shy-Drager syndrome, suggesting a role for CER in the pathology of these diseases.
蛋白別名為：CBLN2; Cerebellin-2;基因ID為：147381；蛋白質ID:Q8IUK8

應用類型: WB，ELISA
補充：最優的抗體稀釋比例需要基于客戶實驗進行優化.建議的起始稀釋比例如下: WB: 1:500-1:2000, ELISA: 1:40000. Not yet tested in other applications.

免疫原: 合成多肽：the C-terminal region of human Cerebellin 2. at AA rangle: 130-210

保存建議: 廠家推薦藍冰運輸.在發貨后能在-20℃保存1年.為最大限度的避免損失，請在打開管蓋之前融化抗體并離心.我們建議使用前分裝以避免反復凍融.
本產品為液體形式,溶解于PBS緩沖液中，含50%甘油，0.5%BSA和0.02%NaN3.

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