CLCNKA is a member of the CLC family of voltage-gated chloride channels. The encoded protein(chloride voltage-gated channel Ka)is predicted to have 12 transmembrane domains, and requires a beta subunit called barttin to form a functional channel. It is thought to function in salt reabsorption in the kidney and potassium recycling in the inner ear. The gene is highly similar to CLCNKB, which is located 10 kb downstream from this gene. Multiple transcript variants encoding different isoforms have been found for CLCNKA.蛋白別名為:CLCNKA; Chloride channel protein ClC-Ka; Chloride channel Ka; ClC-K1;基因ID為:1187;蛋白質ID:P51800
應用類型
WB,ELISA補充:最優的抗體稀釋比例需要基于客戶實驗進行優化.建議的起始稀釋比例如下: WB: 1:500-1:2000, ELISA: 1:40000. Not yet tested in other applications.
免疫原
合成多肽:the C-terminal region of human CLC-KA. at AA rangle: 550-630