EPHB6 encodes a member of a family of transmembrane proteins that function as receptors for ephrin-B family proteins. Unlike other members of this family, the encoded protein(EPH receptor B6) does not contain a functional kinase domain. Activity of this protein can influence cell adhesion and migration. Expression of this gene is downregulated during tumor progression, suggesting that the protein may suppress tumor invasion and metastasis. Alternative splicing results in multiple transcript variants. 蛋白別名為:EPHB6; Ephrin type-B receptor 6; HEP; Tyrosine-protein kinase-defective receptor EPH-6;基因ID為:2051;蛋白質ID:O15197
應用類型
WB,IHC-p,IF,ELISA補充:最優的抗體稀釋比例需要基于客戶實驗進行優化.建議的起始稀釋比例如下: WB: 1:500-1:2000, IHC-p: 1:100-1:300, IF: 1:200-1:1000, ELISA: 1:5000. Not yet tested in other applications.
免疫原
合成多肽:the C-terminal region of human EphB6. at AA rangle: 830-910