Fas-activated serine/threonine kinase encoded by FASTK is a member of the serine/threonine protein kinase family. This kinase was shown to be activated rapidly during Fas-mediated apoptosis in Jurkat cells. In response to Fas receptor ligation, it phosphorylates TIA1, an apoptosis-promoting nuclear RNA-binding protein. The encoded protein is a strong inducer of lymphocyte apoptosis. Two transcript variants encoding different isoforms have been found for this gene. Other variants exist, but their full-length natures have not yet been determined. 蛋白別名為：FASTK; Fas-activated serine/threonine kinase; FAST kinase;基因ID為：10922；蛋白質ID:Q14296
應用類型
WB，ELISA補充：最優的抗體稀釋比例需要基于客戶實驗進行優化.建議的起始稀釋比例如下: WB: 1:500-1:2000. Immunocytochemistry: 1:200-1:1000, ELISA: 1:10000. Not yet tested in other applications.
