Mammalian mitochondrial ribosomal protein L 46 (39S ribosomal protein L46 mitochondrial) is encoded by nuclear gene MRPL46 and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. 蛋白別名為：MRPL46; C15orf4; LIECG2; 39S ribosomal protein L46; mitochondrial; L46mt; MRP-L46; P2ECSL;基因ID為：26589；蛋白質ID:Q9H2W6
應用類型
WB，IHC-p，ELISA補充：最優的抗體稀釋比例需要基于客戶實驗進行優化.建議的起始稀釋比例如下: WB: 1:500-1:2000, IHC-p: 1:100-1:300, ELISA: 1:40000. Not yet tested in other applications.
免疫原
合成多肽：the Internal region of human MRP-L46. at AA rangle: 80-160
