Mammalian mitochondrial ribosomal protein L 50 (39S ribosomal protein L50 mitochondrial) is encoded by nuclear gene MRPL50 and help in protein synthesis within the mitochondrion.Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a putative 39S subunit protein and belongs to the L47P ribosomal protein family. Pseudogenes corresponding to this gene are found on chromosomes 2p, 2q, 5p, and 10q. 蛋白別名為：MRPL50; 39S ribosomal protein L50; mitochondrial; L50mt; MRP-L50;基因ID為：54534；蛋白質ID:Q8N5N7
應用類型
WB，ELISA補充：最優的抗體稀釋比例需要基于客戶實驗進行優化.建議的起始稀釋比例如下: WB: 1:500-1:2000, ELISA: 1:20000. Not yet tested in other applications.
免疫原
合成多肽：the C-terminal region of human MRP-L50. at AA rangle: 90-170
