Nkx2-6 encodes a homeobox-containing protein that belongs to the NK-2 homeobox family. NK2 homeobox is a vertebrate homolog of Drosophila homeobox-containing protein called 'tinman', which has been shown to be essential for development of the heart-like dorsal vessel. In conjunction with related gene, NKX2-5, Nkx2-6 may play a role in both pharyngeal and cardiac embryonic development. Mutations in Nkx2-6 are associated with persistent truncus arteriosus.蛋白別名為:NKX2-6; NKX2F; Homeobox protein Nkx-2.6; Homeobox protein NK-2 homolog F;基因ID為:18092;蛋白質ID:A6NCS4
應用類型
WB,ELISA補充:最優的抗體稀釋比例需要基于客戶實驗進行優化.建議的起始稀釋比例如下: WB: 1:500-1:2000, ELISA: 1:40000. Not yet tested in other applications.
免疫原
合成多肽:the Internal region of human Nkx-2.6. at AA rangle: 60-140