PEX14 encodes an essential component of the peroxisomal import machinery. Peroxisomal biogenesis factor 14 is integrated into peroxisome membranes with its C-terminus exposed to the cytosol, and interacts with the cytosolic receptor for proteins containing a PTS1 peroxisomal targeting signal. Peroxisomal biogenesis factor 14 also functions as a transcriptional corepressor and interacts with a histone deacetylase. A mutation in PEX14 results in one form of Zellweger syndrome蛋白別名為:PEX14; Peroxisomal membrane protein PEX14; PTS1 receptor-docking protein; Peroxin-14; Peroxisomal membrane anchor protein PEX14;基因ID為:5195;蛋白質ID:O75381
應用類型
WB,IHC-p,ELISA補充:最優的抗體稀釋比例需要基于客戶實驗進行優化.建議的起始稀釋比例如下: WB: 1:500-1:2000, IHC-p: 1:100-1:300, ELISA: 1:20000. Not yet tested in other applications.
免疫原
合成多肽:the Internal region of human Peroxin 14. at AA rangle: 90-170