T CLNS1A encodes a protein that functions in multiple regulatory pathways. Chloride nucleotide-sensitive channel 1A complexes with numerous cytosolic proteins and performs diverse functions including regulation of small nuclear ribonucleoprotein biosynthesis, platelet activation and cytoskeletal organization. Chloride nucleotide-sensitive channel 1A is also found associated with the plasma membrane where it functions as a chloride current regulator. Pseudogenes of CLNS1A are found on chromosomes 1, 4 and 6. Several transcript variants encoding different isoforms have been found for CLNS1A.蛋白別名為:CLNS1A; CLCI; ICLN; Methylosome subunit pICln; Chloride channel; nucleotide sensitive 1A; Chloride conductance regulatory protein ICln; I(Cln); Chloride ion current inducer protein; ClCI; Reticulocyte pICln;基因ID為:1207;蛋白質ID:P54105
應用類型
WB,ELISA補充:最優的抗體稀釋比例需要基于客戶實驗進行優化.建議的起始稀釋比例如下: WB: 1:500-1:2000, ELISA: 1:5000. Not yet tested in other applications.
免疫原
合成多肽:the C-terminal region of human pICln. at AA rangle: 160-240