PPP2R3C encodes a regulatory subunit of the serine/threonine phosphatase, protein phosphatase 2. Potein phosphatase 2 regulatory subunit B''gamma is localized to both nuclear and cytoplasmic regions depending on cell cycle phase. Homozygous conditional knockout mice for PPP2R3C exhibit reduced numbers and impaired proliferation of immune system B cells. Potein phosphatase 2 regulatory subunit B''gamma may regulate the expression of the P-glycoprotein ATP-binding cassette transporter through its phosphatase activity. Alternative splicing results in multiple transcript variants.蛋白別名為:PPP2R3C; C14orf10; G5PR; Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma; Protein phosphatase subunit G5PR; Rhabdomyosarcoma antigen MU-RMS-40.6A/6C;基因ID為:55012;蛋白質ID:Q969Q6
應用類型
WB,ELISA補充:最優的抗體稀釋比例需要基于客戶實驗進行優化.建議的起始稀釋比例如下: WB: 1:500-1:2000, ELISA: 1:20000. Not yet tested in other applications.
免疫原
合成多肽:the Internal region of human PPP2R3C. at AA rangle: 140-220