Pre-mRNA splicing occurs in 2 sequential transesterification steps. Pre-mrna processing factor 18 encoded by PRPF18is found to be essential for the catalytic step II in pre-mRNA splicing process. It is found in the spliceosome, and contains seven WD repeats, which function in protein-protein interactions. Pre-mrna processing factor 18 as a sequence similarity to the yeast splicing factor Prp18.蛋白別名為:PRPF18; HPRP18; Pre-mRNA-splicing factor 18; PRP18 homolog; hPRP18;基因ID為:8559;蛋白質ID:Q99633
應用類型
WB,ELISA補充:最優的抗體稀釋比例需要基于客戶實驗進行優化.建議的起始稀釋比例如下: WB: 1:500-1:2000, ELISA: 1:5000. Not yet tested in other applications.
免疫原
合成多肽:the Internal region of human PRPF18. at AA rangle: 160-240