SEPT1 is a member of the septin family of GTPases. Members of this family are required for cytokinesis and the maintenance of cellular morphology.SEPT1 encodes Septin-1 that can form homo- and heterooligomeric filaments, and may contribute to the formation of neurofibrillary tangles in Alzheimer's disease. Alternatively spliced transcript variants have been found but the full-length nature of these variants has not been determined. 蛋白別名為:SEPT1; DIFF6; PNUTL3; Septin-1; LARP; Peanut-like protein 3; Serologically defined breast cancer antigen NY-BR-24;基因ID為:1731;蛋白質ID:Q8WYJ6
應用類型
WB,IHC-p,ELISA補充:最優的抗體稀釋比例需要基于客戶實驗進行優化.建議的起始稀釋比例如下: WB: 1:500-1:2000, IHC-p: 1:100-1:300, ELISA: 1:20000. Not yet tested in other applications.
免疫原
合成多肽:the Internal region of human Septin 1. at AA rangle: 150-230