Decapping is a key step in general and regulated mRNA decay. mRNA-decapping enzyme 1A encoded by DCP1A is a decapping enzyme. This protein and another decapping enzyme form a decapping complex, which interacts with the nonsense-mediated decay factor hUpf1 and may be recruited to mRNAs containing premature termination codons. This protein also participates in the TGF-beta signaling pathway. Alternative splicing of this gene results in multiple transcript variants. 蛋白別名為:DCP1A; SMIF; mRNA-decapping enzyme 1A; Smad4-interacting transcriptional co-activator; Transcription factor SMIF;基因ID為:55802;蛋白質ID:Q9NPI6
應用類型
WB,IHC-p,ELISA補充:最優的抗體稀釋比例需要基于客戶實驗進行優化.建議的起始稀釋比例如下: WB: 1:500-1:2000, IHC-p: 1:100-1:300, ELISA: 1:20000. Not yet tested in other applications.
免疫原
合成多肽:the Internal region of human SMIF. at AA rangle: 80-160