HTR1E (5-Hydroxytryptamine Receptor 1E) is a Protein Coding gene. Diseases associated with HTR1E include attention deficit-hyperactivity disorder. Among its related pathways are Signaling by GPCR and cAMP signaling pathway. GO annotations related to this gene include G-protein coupled receptor activity and serotonin binding. An important paralog of this gene is HTR1F.G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various alkaloids and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity.Serotonin 5-ht1E receptors are primarily located in the frontal cortex, caudate putamen, claustrum, hippocampus, and amygdala. The human 5-ht1E receptor gene has been localized to chromosome 6 (6q14-q15); the receptor is closely related to the serotonin 5-HT1F receptor.蛋白別名為：HTR1E; 5-hydroxytryptamine receptor 1E; 5-HT-1E; 5-HT1E; S31; Serotonin receptor 1E;基因ID為：3354；蛋白質ID:P28566
應用類型
WB，ELISA補充：最優的抗體稀釋比例需要基于客戶實驗進行優化.建議的起始稀釋比例如下: WB: 1:500-1:2000, ELISA: 1:5000. Not yet tested in other applications.
免疫原
合成多肽：the Internal region of human SR-1E. at AA rangle: 70-150
